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NFL odds, lines, picks, spreads, best bets, predictions for Week 12, 2021: Model backing Steelers, Patriots
Nov 28, 2021 | MSN
Picture - NFL odds, lines, picks, spreads, best bets, predictions for Week 12, 2021: Model backing Steelers, Patriots

One of the best things about Thanksgiving is the leftovers, and after Thursday's tripleheader, there are still plenty of intriguing games left on the Week 12 NFL schedule. The surging Indianapolis Colts are three-point underdogs to Tom Brady and the Tampa Bay Buccaneers in the latest NFL odds on Caesars Sportsbook. Later, Cam Newton will try to build off of last week's impressive return to Carolina as a two-point favorite against the Miami Dolphins, per the latest NFL spreads.

Which other NFL matchups offer the best value when looking for the top Week 12 NFL bets and NFL predictions? All of the Week 12 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 12 NFL picks now.

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